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Index > Protein center > Fasn(Gene name) > Mouse
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  • Fasn (Gene name),
  • Fatty acid synthase (Protein name ),  FAS_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Fasn;
    Protein name:
    Fatty acid synthase;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer which is arranged in a head to tail fashion.
    Function:
    Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
    Subcellular Location:
    Cytoplasm Melanosome
    Protein Attributes:
    Sequence length:
    2504
    Sequence:
    50:
    MEEVVIAGMS | GKLPESENLQ | EFWANLIGGV | DMVTDDDRRW | KAGLYGLPKR | 
    100:
    SGKLKDLSKF | DASFFGVHPK | QAHTMDPQLR | LLLEVSYEAI | VDGGINPASL | 
    150:
    RGTNTGVWVG | VSGSEASEAL | SRDPETLLGY | SMVGCQRAMM | ANRLSFFFDF | 
    200:
    KGPSIALDTA | CSSSLLALQN | AYQAIRSGEC | PAALVGGINL | LLKPNTSVQF | 
    250:
    MKLGMLSPDG | TCRSFDDSGS | GYCRSEAVVA | VLLTKKSLAR | RVYATILNAG | 
    300:
    TNTDGSKEQG | VTFPSGEVQE | QLICSLYQPA | GLAPESLEYI | EAHGTGTKVG | 
    350:
    DPQELNGITR | SLCAFRQAPL | LIGSTKSNMG | HPEPASGLAA | LTKVLLSLEH | 
    400:
    GVWAPNLHFH | NPNPEIPALL | DGRLQVVDRP | LPVRGGNVGI | NSFGFGGSNV | 
    450:
    HVILQPNTRQ | APAPTAHAAL | PHLLHASGRT | LEAVQDLLEQ | GRQHSQDLAF | 
    500:
    VSMLNDIAAT | PTAAMPFRGY | TVLGVEGRVQ | EVQQVSTNKR | PLWFICSGMG | 
    550:
    TQWRGMGLSL | MRLDSFRESI | LRSDEAVKPL | GVKVSDLLLS | TDERTFDDIV | 
    600:
    HAFVSLTAIQ | IALIDLLTSV | GLKPDGIIGH | SLGEVACGYA | DGCLSQREAV | 
    650:
    LAAYWRGQCI | KDAHLPPGSM | AAVGLSWEEC | KQRCPAGVVP | ACHNSEDTVT | 
    700:
    ISGPQAAVNE | FVEQLKQEGV | FAKEVRTGGL | AFHSYFMEGI | APTLLQALKK | 
    750:
    VIREPRPRSA | RWLSTSIPEA | QWQSSLARTS | SAEYNVNNLV | SPVLFQEALW | 
    800:
    HIPEHAVVLE | IAPHALLQAV | LKRGVKSSCT | IIPLMKRDHK | DNLEFFLTNL | 
    850:
    GKVHLTGINV | NPNALFPPVE | FPAPRGTPLI | SPHIKWDHSQ | TWDVPVAEDF | 
    900:
    PNGSSSSSAT | VYSIDASPES | PDHYLVDHCI | DGRVIFPGTG | YLCLVWKTLA | 
    950:
    RSLGLSLEET | PVVFENVSFH | QATILPKTGT | VALEVRLLEA | SHAFEVSDTG | 
    1000:
    NLIVSGKVYL | WEDPNSKLFD | HPEVPTPPES | ASVSRLTQGE | VYKELRLRGY | 
    1050:
    DYGPQFQGIC | EATLEGEQGK | LLWKDNWVTF | MDTMLQVSIL | GSSQQSLQLP | 
    1100:
    TRVTAIYIDP | ATHRQKVYRL | KEDTQVADVT | TSRCLGITVS | GGIHISRLQT | 
    1150:
    TATSRRQQEQ | LVPTLEKFVF | TPHMEAECLS | ESTALQKELQ | LCKGLARALQ | 
    1200:
    TKATQQGLKA | AMLGQEDPPQ | HGLPRLLAAA | CQLQLNGNLQ | LELGEALAQE | 
    1250:
    RLLLPEDPLI | SGLLNSQALK | ACVDTALENL | STLKMKVAEV | LAGEGHLYSR | 
    1300:
    IPALLNTQPM | LQLEYTATDR | HPQALKDVQT | KLQQHDVAQG | QWNPSDPAPS | 
    1350:
    SLGALDLLVC | NCALATLGDP | ALALDNMVAA | LKEGGFLLVH | TVLKGHALGE | 
    1400:
    TLACLPSEVQ | PAPSLLSQEE | WESLFSRKAL | HLVGLKRSFY | GTALFLCRRA | 
    1450:
    IPQEKPIFLS | VEDTSFQWVD | SLKSTLATSS | SQPVWLTAMD | CPTSGVVGLV | 
    1500:
    NCLRKEPGGH | RIRCILLSNL | SNTSHAPKLD | PGSPELQQVL | KHDLVMNVYR | 
    1550:
    DGAWGAFRHF | QLEQDKPKEQ | TAHAFVNVLT | RGDLASIRWV | SSPLKHTQPS | 
    1600:
    SSGAQLCTVY | YASLNFRDIM | LATGKLSPDA | IPGKWASRDC | MLGMEFSGRD | 
    1650:
    RCGRRVMGLV | PAEGLATSVL | LSSDFLWDVP | SSWTLEEAAS | VPVVYTTAYY | 
    1700:
    SLVVRGRIQR | GETVLIHSGS | GGVGQAAISI | ALSLGCRVFT | TVGSAEKRAY | 
    1750:
    LQARFPQLDD | TSFANSRDTS | FEQHVLLHTG | GKGVDLVLNS | LAEEKLQASV | 
    1800:
    RCLAQHGRFL | EIGKFDLSNN | HPLGMAIFLK | NVTFHGILLD | ALFEEANDSW | 
    1850:
    REVAALLKAG | IRDGVVKPLK | CTVFPKAQVE | DAFRYMAQGK | HIGKVLVQVR | 
    1900:
    EEEPEAVLPG | AQPTLISAIS | KTFCPAHKSY | IITGGLGGFG | LELARWLVLR | 
    1950:
    GAQRLVLTSR | SGIRTGYQAK | HIREWRRQGI | QVLVSTSNVS | SLEGARALIA | 
    2000:
    EATKLGPVGG | VFNLAMVLRD | AMLENQTPEL | FQDVNKPKYN | GTLNLDRATR | 
    2050:
    EACPELDYFV | AFSSVSCGRG | NAGQTNYGFA | NSTMERICEQ | RRHDGLPGLA | 
    2100:
    VQWGAIGDVG | IVLEAMGTND | TVIGGTLPQR | ISSCMEVLDL | FLNQPHAVLS | 
    2150:
    SFVLAEKKAV | AHGDGDTQRD | LVKAVAHILG | IRDLAGINLD | STLADLGLDS | 
    2200:
    LMGVEVRQIL | EREHDLVLPM | REVRQLTLRK | LQEMSSKTDS | ATDTTAPKSR | 
    2250:
    SDTSLKQNQL | NLSTLLVNPE | GPTLTQLNSV | QSSERPLFLV | HPIEGSTTVF | 
    2300:
    HSLAAKLSVP | TYGLQCTQAA | PLDSIPNLAA | YYIDCIKQVQ | PEGPYRIAGY | 
    2350:
    SFGACVAFEM | CSQLQAQQGP | APTHNNLFLF | DGSHTYVLAY | TQSYRAKMTP | 
    2400:
    GCEAEAEAEA | LCFFIKQFLD | VEHSKVLEAL | LPLKSLEDRV | AASVDLITKS | 
    2450:
    HHSLDRRELS | FAAVSFYHKL | RAADQYKPKA | KYHGNVTLLR | AKTGGTYGED | 
    2500:
    LGADYNLSQV | CDGKVSVHII | EGDHRTLLEG | SGLESIINII | HSSLAEPRVS | 
    2504:
    VREG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Fatty acid synthase
    Cat.:
    E1451m
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    96T
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    ELISA Kit for Mouse Fatty acid synthase
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    E1451h
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    96T
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    ELISA Kit for Mouse Fatty acid synthase
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    E1451r
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    96T
    ELISA Kit for Mouse Fatty acid synthase
    Cat.:
    E1451b
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    96T
    ELISA Kit for Mouse Fatty acid synthase
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    E1451c
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    ELISA Kit for Mouse Fatty acid synthase
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    CLIA Kit for Mouse Fatty acid synthase
    Cat.:
    U1451m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Fatty acid synthase
    Cat.:
    U1451r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Fatty acid synthase
    Cat.:
    U1451h
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    Packing:
    96T
    CLIA Kit for Mouse Fatty acid synthase
    Cat.:
    U1451c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Fatty acid synthase
    Cat.:
    U1451b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Fatty acid synthase
    MSDS:
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    Polyclonal Antibody for Mouse Fatty acid synthase
    Cat.:
    P1451Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Fatty acid synthase
    Polyclonal Antibody for Mouse Fatty acid synthase
    Cat.:
    P1451Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Fatty acid synthase
    Polyclonal Antibody for Mouse Fatty acid synthase
    Cat.:
    P1451Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Fatty acid synthase
    Monoclonal Antibody for Mouse Fatty acid synthase
    Monoclonal Antibody for Mouse Fatty acid synthase
    Monoclonal Antibody for Mouse Fatty acid synthase
    Monoclonal Antibody for Mouse Fatty acid synthase
    Monoclonal Antibody for Mouse Fatty acid synthase
    Monoclonal Antibody for Mouse Fatty acid synthase
    Protein for Mouse Fatty acid synthase
    Protein for Mouse Fatty acid synthase
    Protein for Mouse Fatty acid synthase
    Protein for Mouse Fatty acid synthase
    Protein for Mouse Fatty acid synthase
    Protein for Mouse Fatty acid synthase

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    Precision
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    Linearity
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    References
    1. 1.
      "Involvement of fatty acid synthase in axonal development in mouse embryos."
      Ueno K.
      Genes Cells5:859-869(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6J.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Brain.
      tissue: Liver.
    4. 4.
      Bienvenut W.V.
      Submitted (2005-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-12; 225-235; 299-310; 385-409; 469-478; 1252-1270; 1333-1344; 1388-1398; 1501-1508; 1705-1717; 1733-1745; 2124-2132; 2376-2384 AND 2476-2498;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
      strain: C57BL/6.
      tissue: Liver.
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1527-2504
      strain: C57BL/6J.
      tissue: Thymus.
    6. 6.
      "Structure of mouse fatty acid synthase mRNA. Identification of the two NADPH binding sites."
      Paulauskis J.D. , Sul H.S.
      Biochem. Biophys. Res. Commun.158:690-695(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1666-2504
      strain: CD-1.
      tissue: Liver.
    7. 7.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-59; LYS-790; LYS-993; LYS-1071; LYS-1276; LYS-1840 AND LYS-2384;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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